In the cell cycle replication of the genome occurs in the

In the cell cycle, replication of the genome occurs during the S phase (Synthesis phase). During this phase, the cell's DNA is replicated, resulting in the duplication of the genetic material. The S phase follows the G1 (Gap 1) phase and precedes the G2 (Gap 2) phase. Replication of the genome is a crucial step in preparation for cell division, ensuring that each daughter cell receives an identical copy of the genetic material.